تستخدم مطهرات الارضيات ومطهرات الايدي على نطاق واسع في المستشفيات ومرافق الرعاية الصحية الأخرى لمجموعة متنوعة من التطبيقات. ومع ذلك، لا يتم دائما ذكر فعاليتها المضادة للبكتيريا بشكل جيد من قبل المنتجين والمستهلكين حيت يجدون صعوبة في اختيار المنتج المناسب وفقا لاحتياجاتهم. لذلك، كان الهدف من هذه الدراسة تقييم فعالية التضاد البكتيري لمطهرات الارضيات ومطهرات الايدي المختارة من مركز طرابلس الطبي باعتباره أحد اهم المستشفيات الليبية.  أربعة عشر (14) نوعا من مطهرات الارضيات ومطهرات الايدي.(Dex36, Dex50, Dex53, Mzid-S, Mzid-AF, Deson-AF, Dettol, Seem, Chlor and Wipol, HiBi, Esept, Emed and Desman) . تم تقييمها باستخدام أربعة أنواع من التجارب المعملية العيارية وهي: (capacity test, diffusion test, in-use test and suspension test) ضد ستة من السلالات البكتيرية ، ثلاثة من البكتيريا إيجابية الجرام وثلاثة من البكتيريا سالبة الجرام.(Bacillus cereus, Staphylococcus haemolyticus, Staphylococcus aureus, Klebscilla pneumonia, Acinetobacter baumannii, and Pseudomonas aeruginosa). هذه السلالات تم عزلها من بيئات مختلفة من اقسام مركز طرابلس الطبي ، وقد تم دراسة حساسيتها لمطهرات الارضيات ومطهرات الايدي بتراكيز مختلفة و فترات تحضين مختلفة ، وأظهرت النتائج أن استخدام التراكيز الموصى بها من مركبات (Dex 50 & 53 and Deson-AF) كان لها تأثير كبير على تثبيط الأنواع البكتيرية التالية:Bacillus cereus, Staphylococcus haemolyticus, staphylococcus aureus, Klebsiella pneumonia, Acinetobacter baumannii, and Pseudomonas aeruginosa..تشير النتائج الإجمالية ان مركبات (Dex50 & 53, Mzid-S, Mzid-AF, HiBi) عد استخدامها وفق التخفيفات الموصى بها ، كانت الأفضل كمطهرات ضد البكتيريا التالية:Bacillus cereus, Staphylococcus aemolyticus, staphylococcus aureus, Klebsiella pneumonia, Acinetobacter baumannii, and Pseudomonas aeruginosa إن الاستخدام الجيد والصحيح للمطهرات ضروري لتجنب الإصابة بالأمراض التي قد تنشأ من جراء انتشار مثل هده الميكروبات الممرضة. Abstract Biocides (disinfectants and antiseptics) are used extensively in hospitals and other health care settings for a variety of applications. However, their .ntibacterial effectiveness is not always well stated by the manufacturers and consumers find it difficult to choose the right product according to their .eeds. Therefore, the aim of this study was to evaluate practically achieves disinfection efficacy of locally available disinfectants and antiseptics on surfaces and infectious microbiological utilities of Tripoli Medical Center (TMC). Fourteen biocides; Ten disinfectants (Dex36, Dex50, Dex53, Mzid-S, Mzid-AF, Deson, Dettol, Seem, Chlor and Wipol) and four antiseptics (HiBi, Esept, Emed and Desman) were tested at concentrations .commended by manufacturers on surfaces, walls and different utilities that were ontaminated by locally circulating six isolates of .cilluscereus,Staphylococcus haemolyticus, staphylococcus aureus, Klebscilla pneumonia, Acinetobacter baumannii, and Pseudomonas aeruginosa using four standard evaluation test procedures (capacity test, diffusion test, in-use test and suspension test). Results showed the highest average log reduction (7.4) of test bacteria was given by quaternary ammonium based disinfectants; Dex50, Dex53, Deson-AF and Mzid-S. A comparable average log reduction of test bacteria was noted (7.0, 7.2 and 7.3) for Deson-AF, Dex.50 and Dex.53 respectively. In contrast HiBi as an alcoholic based antiseptic gave the highest average log reduction (7.2) gainst tested bacteria. Desman, Emed and Wipol antiseptics had poor antibacterial activity on tested bacteria causing almost undetectable log reduction in cell viability. From contamination point of view, five critical departments in Tripoli Medical Centre (TMC) namely; Neonatal Intensive Care Unit (ICU), Surgical ICU, Dermatology, Oncology, and Urology departments were found contaminated with six types of bacteria. Bacillus cereuses followed by lebscilla pneumonia were the most bacteria spread in whole five mentioned departments, particularly in dermatology department. Staphylococcus haemolyticus was next most widespread bacterium and almost isolated qually from the five medical departments. Acinetobacter baumannii had been isolated from Neonatal ICU; whereas Staphylococcus aureus and seudomonas aeruginosa had been isolated from Oncology Department and Surgical ICU respectively. In addition, Dex36, Chlor, Chlor, Wipol, Desman and E-med exhibited bacterial contaminationin both capacity and in-use ests.
آمال منصور إبراهيم (2016)

More than 2000 cultivars of Phoenix dactylifera L. are known to grow around the world. Date is an essential fruit in North Africa, and in Libya in particular, it represents an important national food resource. Recently, researchers discovered the medicinal value of different parts of palm tree beside the well known nutritional value of the fruit edible part. In this study five Libyan date seeds (Bestian, Deglet, Abel, Khadrai and Hamrai) were collected from Aljofra region and were screened for phytochemical components and their antimicrobial activity. The phytochemical analysis of methanolic extract of five different Libyan date palm seeds showed the presence of aflavnoids, glycosides, phytosterols, phenolic compound, tannins, and fixed oil, absences of alkaloids and saponine. The susceptibility of bacterial species to five methanolic extracts of Phoenix dactylifera L seeds by cup-cut agar method exhibited Inhibition zones (IZD). That inhibition zone diameters are vary from 15.0 0.3 to 3.02 0.01 against MRSA; 16.040.1 to 6.0  0.7 against Pseudomonas aeruginosa; 14.2 0.1 to 6.00.7 against Proteus vulgaris; 18.3 0.2 to 6.0 0.1 against Staphylococcus aureus; 14.04 0.2 to 2.0 0.02 against E. coli; and 18.0 0.1 to3.2 0.02 against Klebsiella pneumonia. The results of current study shows the antibacterial properties of five Libyan samples of date seed extract against a wide spectrum of bacteria. arabic 21 English 126
Basma Doro, Nahla Labyad, Fadia Gafri(1-2020)

Aims: The study is intended to compare the freshly collected henna (Lawsonia inermis L.) and the market henna in term of microscopical key elements and heavy metals contamination. Moreover, this study is aimed to investigate the effect of henna and its oily additives on kidney histology in female mice. Study Design: Department of Pharmacognosy, Faculty of Pharmacy, University of Tripoli and Animals House, Biotechnology Research Center in 2010. Methodology: The powders of collected and market henna have been subjected to a microscopical study with magnification of 5x then 40 x to investigate the henna key elements, which are calcium oxalate clusters, anomocytic stomata, starch grains and fibers. Three elements: arsenic (As), mercury (Hg) and lead (Pd) were analyzed by atomic absorption spectroscopy (AAs) for the collected and market henna. For histopathological study, an aqueous extracts of L. inermis leaves and L. inermis leaves-oils were prepared by maceration. Eighteen female Albino Wister mice (3-4-months, 20-25 gm) were injected with the prepared extracts subcutaneously by dose 50 ml/kg/day for 5 days. Kidneys were collected and subjected to histopathological study. Results: From this study, the microscopical investigation exhibited the presence of some elements which are never mentioned as the henna key elements. Both market and collected henna were contaminated with a high level of heavy metals specially lead (Pd). The histopathological findings implied that there are many histological changes on the kidney tissues such as aggregation of round cells and congestion of blood vessels. Conclusion: The market henna might be adulterated with other types of plant. The presence of a high concentration of lead (Pd) in the collected henna as well as the market henna might be considered as the cause of some L. inermis adverse effects. L. inermis leaves and L. inermis leaves-oils aqueous extracts implied many abnormalities in the kidney tissues. arabic 17 English 102
Sakina S. Saadawi, Hanin N. Mughrbi, Mukhtar R. Haman, Surur A. Ahmed, Laila A. Ghashout, Elsayed R. Elattar(5-2020)