كلية الصيدلة

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حول كلية الصيدلة

تأسست كلية الصيدلة سنة 1975م وتعتبر الكلية الأقدم في ليبيا للعلوم الصيدلانية، تهدف منذ بداية تأسيسها إلى المساهمة في الرفع من مستوى الخدمات الصحية للمواطن بليبيا والبدء جدياً في تطوير الخدمات الدوائية والدخول في هذا المجال على أسس علمية وبعد مُضي ما يزيد عن ثمانية وثلاثين عاماً على مولد هذه القلعة العلمية، لازالت هذه المؤسسة تزود المجتمع بشباب مؤهل ومؤمن بدوره في ليبيا الحرة ليقود مجالات الصناعة والرقابة الدوائية والتحاليل الطبية وترشيد استعمال الأدوية والاستفادة القصوى من الأعشاب والنباتات الطبية وبدأت الدراسة بالكلية مع بداية العام الدراسي 1976/1975م. واستمرت الدراسة بالمبنى القديم والذي تشغله الآن كلية الإعلام والفنون. وفي العام 1983م، تـــم إبـــرام عقد إنشاء مبنى جديد لكلية الصيدلة بجامعة طرابلس. وقد تم بناؤه على مساحــة تبلغ أربعـين آلف متر مربع “ 40.000 م2 “جنوب جامعة طرابلس. ويعتبر مبنى الكلية من أجمل مباني الجامعة حيث تم اختياره كأحد أجمل المباني التعليمية في العالم حسب تقرير أعدتـه المنظـــمة العــالمية للثقافــة والعلــــوم “اليونسكو“. يحد الكلية من ناحية الشرق كلية الطب البشرى لتشكل مع مركز طرابلس الطبي نموذجاً متميزاً للكليات الطبية التخصصية. هذه المؤسسة لا تزال ترعى منسبيها من الطلاب ليكونوا صيادلة المستقبل ولكي يشاركوا في بناء ليبيا.

حقائق حول كلية الصيدلة

نفتخر بما نقدمه للمجتمع والعالم

79

المنشورات العلمية

110

هيئة التدريس

1163

الطلبة

3188

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أ. إيمان علي المبروك دياب

ايمان علي دياب هي احد اعضاء هيئة التدريس بقسم الصيدلانيات بكلية الصيدلة. تعمل السيدة ايمان علي دياب بجامعة طرابلس كعضو هيئة تدريس منذ 01-09-2017 ولها العديد من المنشورات العلمية في مجال تخصصها

منشورات مختارة

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Phyto-pharmaceuticals and biological study on graviola (Annona muricata L.) fruit and dietary supplement of graviola sold on the Libyan market as a cancer cure against TCA induce hepatotoxicity in mice

Annona muricata (Graviola) has many medicinal properties and used widely in traditional medicine for treatment various disorders. The present study was conducted to evaluate phytochemical and quality control (QC) of random sample of graviola dietary supplement capsules (DS) which sold in the Libyan market as anticancer product. As well as the present work designed to evaluate heatoprotective effects of aqueous extract of graviola fruit pulp or aqueous DS of graviola capsules against trichloroacetic acid (TCA) induced hepatotoxicity in albino mice. Quality control parameters were determined on random samples of graviola DS using standard methods. A total of 120 female mice were divided into 6 groups and were used for biological screening to determine biochemical and histopathological alteration in liver of mice treated with TCA with or without aqueous extract of A.muricata fruit pulp or DS of graviola. The results of quality control and phytochemical screening revealed that all quality control tests conducted on the random sample of DS capsules of graviola were within normal values according to the standards of the Quality Control Center for Pharmaceuticals in Tripoli, only few samples showed slight increase in the moisture content. However, all samples appeared free from microbial contamination. While, growth of fungal contamination (Pencillium Spp) in the same samples were detected but all samples appeared free from aflatoxins contamination. Also, all samples were free from industrial radioactive contamination. Phytochemical study revealed presence of alkaloids, tannins, steroids, glycosides, falvonoids, anthraquinones, saponin and coumarins in extracts of graviola fruit pulp and graviola DS capsules. However, absence some phytochemical components in DS capsules was detected. The result of biological screening revealed that no clinical signs and abnormalities in behavior and external feature in mice treated with aqueous extract of graviola fruit pulp or aqueous extract of graviola DS capsules. However, the treatment with aqueous extract of graviola fruit pulp and DS of graviola reduced the abnormal changes in behavior and external features in female mice intoxicated with TCA, markedly reduced the mortality in TCA administrated mice and induced slight improvement in the final body weight comparing to TCA only intoxicated group. Biochemical study revealed that administration of aqueous extract of graviola fruit pulp or aqueous extract of DS of graviola significantly decreased the elevated serum activities of AST and ALT compared to TCA only intoxicated mice. Histological examination revealed that administration of aqueous extract of graviola fruit plup or aqueous extract of DS of graviola with TCA induced ameliorative changes and disappearance of the most pathological changes in the liver tissue compared to of TCA only intoxicated mice and the ameliorating changes were more obvious in the mice treated with aqueous extracts of DS of graviola and TCA. The present results demonstrate that A. muricata play an important role in the protection against TCA induced hepatotoxicity. It can be concluded that the present study provide some pharmacological and therapeutical informations about extract of the graviola fruit pulp and DS of graviola capsules which can use in future investigations and applications and demonstrated presence of important phyochemical constituents in the graviola fruit pulp extract and DS of graviola capsules. The extract of the graviola fruit pulp and DS of graviola capsules have protective effects against TCA induced liver toxicity in mice. arabic 33 English 168
Ajlal A. A. Alzergy, Mukhtar R. Haman, Muftah A. M. Shushni, , Fairouz A. Almagtouf (2-2018)
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Green Synthesis and Characterization of Libyan Propolis Nanoparticles and its Biological Activity

Abstract: The ever-increasing demand for natural products and biotechnology, derived from bees and ultramodernization of various analytical devices, has facilitated the rational and planned development of biotechnology products with a focus on human health to treat chronic and neglected diseases. This study aimed to prepare, characterize and examine the stability and evaluation of the antioxidant and the antibacterial activity of Libyan propolis. Propolis Nanoparticles PNP were prepared using particle size reduction, then Transmission Electron Microscope (TEM) at a magnification of X 25000, was used for accurate evaluation of the size distribution of NPs. Three different concentration (10, 5, 2.5 mg/ml) of propolis and nano-propolis powder were tested for their 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity. The quantitative antioxidant activity test results using UV Spectrophotometer absorbance at 517 nm. The antibacterial activities of propolis and prepared nano propolis at different concentrations (10, 5 and 2.5mg/ml) were tested on bacterial strain, Klebsiella, human mouth, skin, and surface bacteria using cup cut diffusion method. The findings exhibited that the prepared propolis Nanoparticles (PNPs) were generally non-spherical with a size 100-200 nm. The PNP was a nano-sized particle around 316 nm in diameter. Zeta potential of PNP showed a negative surface charge value (− 48 mV) which was sufficiently high to avoid NPs aggregation. This value represents a stable and dispersed suspension of NPs and disables the tendency of aggregations in a short in period of time. Poly dispersity index (PdI) of synthetized PNP was used as a measurement of the size distribution. PdI values for PrNP were generally uniform with PdI 0.3 indicating monodispersity of the prepared systems. The propolis and PNPs displayed good antioxidant activity with inhibition percentage (77%, 46% and 18%) for propolis and (82%, 66% and 37%) for PNPs. Propolis nanoparticles showed to have more antibacterial effect compared to propolis. Libyan propolis nanoparticles has shown to be potential candidates as antioxidant and antibacterial agent.
Hanin Nafed . Mughrbi, Sakina Salem Mohammed Saadawi, Bushra M. Dakhil, Rokaya O. Amara, Riham M. El-Moslemany, Khadija O. Turkman, Masarra A. Daraweel, , Khairi A. Alennabi, Rabia Omar abdullah Alghazeer(4-2022)
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Effect of Tamoxifen on Ethanol Induced Gastric Ulcer in Rats

Background: Tamoxifen is selective estrogen receptor modulators, used in treatment of breast cancer, some literatures reported its impact on the process of peroxidation. Aim: The aim of this study was to evaluate the effect of tamoxifen on ethanol induced gastric ulcer in rats. Method: Gastric ulcers were induced in Wistar albino rats by oral administration of absolute alcohol (1 ml/200 g). Antiulcer activity of tamoxifen (0.5 and 10 mg/kg, p.o.) was observed and compared to standard drug (omeprazole 20mg/kg, p.o.), the ulcer index, ulcers numbers, lengths, gastric volume and total gastric acidity were evaluated. Histopathology is performed for confirmation. Results: Tamoxifen in 10mg/kg dose produced a highly significant (P
Malak jafari, Al-Asayed R. Al-Attar(4-2021)
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