كلية الصيدلة

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حول كلية الصيدلة

تأسست كلية الصيدلة سنة 1975م وتعتبر الكلية الأقدم في ليبيا للعلوم الصيدلانية، تهدف منذ بداية تأسيسها إلى المساهمة في الرفع من مستوى الخدمات الصحية للمواطن بليبيا والبدء جدياً في تطوير الخدمات الدوائية والدخول في هذا المجال على أسس علمية وبعد مُضي ما يزيد عن ثمانية وثلاثين عاماً على مولد هذه القلعة العلمية، لازالت هذه المؤسسة تزود المجتمع بشباب مؤهل ومؤمن بدوره في ليبيا الحرة ليقود مجالات الصناعة والرقابة الدوائية والتحاليل الطبية وترشيد استعمال الأدوية والاستفادة القصوى من الأعشاب والنباتات الطبية وبدأت الدراسة بالكلية مع بداية العام الدراسي 1976/1975م. واستمرت الدراسة بالمبنى القديم والذي تشغله الآن كلية الإعلام والفنون. وفي العام 1983م، تـــم إبـــرام عقد إنشاء مبنى جديد لكلية الصيدلة بجامعة طرابلس. وقد تم بناؤه على مساحــة تبلغ أربعـين آلف متر مربع “ 40.000 م2 “جنوب جامعة طرابلس. ويعتبر مبنى الكلية من أجمل مباني الجامعة حيث تم اختياره كأحد أجمل المباني التعليمية في العالم حسب تقرير أعدتـه المنظـــمة العــالمية للثقافــة والعلــــوم “اليونسكو“. يحد الكلية من ناحية الشرق كلية الطب البشرى لتشكل مع مركز طرابلس الطبي نموذجاً متميزاً للكليات الطبية التخصصية. هذه المؤسسة لا تزال ترعى منسبيها من الطلاب ليكونوا صيادلة المستقبل ولكي يشاركوا في بناء ليبيا.

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نفتخر بما نقدمه للمجتمع والعالم

70

المنشورات العلمية

106

هيئة التدريس

1163

الطلبة

0

الخريجون

البرامج الدراسية

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يوجد بـكلية الصيدلة أكثر من 106 عضو هيئة تدريس

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د. أمينة محمد ابوبكر المرزوقي

أمينة المرزوقي هي احد اعضاء هيئة التدريس بقسم الصيدلة الصناعية بكلية الصيدلة. تعمل السيدة أمينة المرزوقي بجامعة طرابلس كـاستاذ مساعد منذ 2016-01-24 ولها العديد من المنشورات العلمية في مجال تخصصها

منشورات مختارة

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Physical Properties, Antibacterial and Antioxidant Properties of Raw South Africa Shea Butter against Samples from Libyan Market

Vigorous research has been conducted into the phenology of the shea tree, its usage and that of the shea butter extracted from the nuts of the shea fruit. Shea butter is the most valuable product in the Shea tree and its use as raw or in cosmetic and pharmaceutical products was expanded in the last years. The aim was to carry out comparative study between imported South African raw Shea Butter, one sample from Poland and samples from Libyan market on their physical properties (organoleptic), thin layer chromatography (TLC) chromatogram, phytochemical screening and diphenylpicrylhydrazil (DPPH) scavenging activity. As well as antimicrobial screening. Organoleptic test was carried out by comparing color and odor. TLC chromatogram was performed by spotting solution of samples in hexane on TLC plate and eluted twice in hexane: ethylacetate 8:2 to get good separation. Phytochemical screening was performed to determine the presence of carbohydrates (Fehling test), steroids, and triterpens (Salkwiski test). DPPH assay was carried out by spraying TLC sample spots by 0.2% DPPH methanolic solution. Antimicrobial test was conducted on Pseudomonas aeruginosa and Staphylococcus aureus. Mueller-Hinton agar was used with ciprofolxacin as +ve control and DMSO as–ve control. As a result, Shea Butter samples showed wide diversity in color and odor which considered normal except two white samples that might undergo refining process, while spreadability and TLC chromatograms were similar. Samples and control showed presence of carbohydrates, steroids and triterpens. Control and samples had DPPH scavenging activity. Shea Butter control and samples had no antimicrobial activities against P. aeruginosa and S. aureus. arabic 17 English 111
Sakina Salem Saadawi, Khairi Ali Alennabi, Hanin Nafed Mughrbi, Kholoud Lotfi, Nesrin Saleh Ali Abdulnabi(4-2020)
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Antioxidant and Antibacterial Effect of Vitis labrusca, Vitis vinifera and Vitis vinifera Seeds Extract

Grape seeds extract has therapeutic values including antimicrobial activity, antioxidant effect, wound healing and prevention of cardiovascular diseases. This study aimed to evaluate and compare antibacterial activity of different species of grape seed) Vitis labrusca, Vitis vinifera and Vitis vinifera( against some bacterial strains (Staphylococcus aureus, Streptococcus pneumonia, Acinetobacter Calcoaceticus, Klebsiella pneumoniae and Escherichia coli). Determine antioxidant effect of grape seed extracts (qualitatively). Antibacterial effects was performed using agar cup cut diffusion method for all bacterial species, followed by using minimum inhibitory concentration MIC for the species showed to be inhibited by grape seeds extracts. Antioxidant assay was done using DPPH scavenging test, methanolic solution of each grape seeds was spotted on TLC paper, sprayed with 0.2 % methanolic solution of diphenyl picryl hydrazyl (DPPH) reagent. Vitamin C was used as positive control. From the results, all grape species didn’t have any effect on K. pneumonia and E. coli, red and black grape seeds showed the highest inhibition zone (20 mm) on Staph. Aureus agar plate, green grape had the highest effect on Sterp. Pneumonia agar plate (20 mm). The lowest effect was for the red grape seeds extract (13 mm) on Acinetobacter calciaceticus. In general the three grape seeds extract had effect on Staph. aureus, Sterp. pneumonia and Acinetobacter calciaceticus. The red and black grape seed extract was effective against Sterp. pneumonia strain at MIC values of 7.8 mg/mL and black grape seeds extract had MIC at 7.8 mg/mL on Staph. aureus. However, the test for MIC of seeds extracts for the rest of bacterial species ranged between 15.62 and 87.5 mg/mL. The result showed that black grape seeds extract had the largest spot change in color indicating strong antioxidant effect. The lowest effect was by red grape seeds. From this result black grape showed to be the best grape seeds extract among the three chosen species in its antibacterial and antioxidant efficacy.
Sakina Salem Mohammed Saadawi(4-2021)
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Effect of Ion Channel Blockers on the Pharmacological Action of Paracetamol Using Albino Mice

Paracetamol is one of the most widely used drug as antipyretic and analgesic for mild to moderate pain. Currently, paracetamol is the first-line choice for pain management and antipyresis. Ion channels are pore-forming proteins that allow the flow of ions across membranes and involved in many cellular processes; drugs acting on ion channels have long been used for the treatment of many diseases. Objective: To estimate the effect of voltage gated ion channel blockers on analgesic activity of Paracetamol and explore the interaction between ion channel blockers and paracetamol on pain behaviour. Materials and Methods: Male albino mice were used. The central antinociceptive activity was determined by hot plate test and formalin test (Phase I; neuropathic pain). Antiinflammatory activity was determined by formalin test (Phase II). Intraperitoneal injection was adopted. Five groups of mice were used. Group 1; control group (1% T80), group 2; treated with (200mg/kg) paracetamol, group 3; treated with different drugs of ion channel blockers, group 4; received standard drugs, Aspirin (200mg/kg) for formalin test (phase II) or tramadol (5mg/kg) for hot plate test and formalin test (phase I), group 5; received combined treatment of ion channel blockers and paracetamol. Results: Pain produced by noxious stimuli (heat and formalin) was significantly reduced by acute administration of paracetamol. Inflammation pain produced by formalin injection was significantly decreased by acute administration of paracetamol. Acute administration of nifedipine showed significant decrease in nociception and inflammation pain. Combined treatment of nifedipine and paracetamol produced antinociceptive and anti-inflammatory activity but less than the additive effect. Verapamil has no analgesic effect in the two models, and did not change the affect of paracetamol analgesic activity when administered together. Phenytoin produces significant decrease in nociceptive pain using hot plate but not in formalin test (Phase I), and produce significant decrease in inflammatory pain (Phase II). The combined treatment of phenytoin and paracetamol showed analgesic activity less than the additive effect. 4-Aminopyridine produces significant antinociceptive and anti-inflammatory activity. The combined administration of 4-aminopyridine and paracetamol showed analgesic activity, which is less than the additive effect using formalin test, while paracetamol analgesic activity is potentiated by 4-aminopyridine using hot plate test. Conclusion: Paracetamol has antinociception and anti-inflammatory activity on pain model used (Hot plate test and Formalin test). Ion channel blockers produce antinociception and anti-inflammatory activity. Verapamil has no effect on nociception or inflammation pain and no effect on paracetamol analgesic activity. Nifedipine, phenytoin and 4-aminopyridine interact with paracetamol producing less additive analgesic effect, except 4-aminopyridine in thermal stimuli (Hot plate) is more sensitive compared to chemical stimuli (formalin test – phase I), where potentiates paracetamol action.
هناء مدحت الزقلعي (2014)
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