Department of Pharmacology, Toxicology & Forensic Medicine

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Department of Pharmacology, Toxicology & Forensic Medicine has more than 7 academic staff members

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Prof.Dr. Marwan Mustafa Ali Draid

مروان دريد هو احد اعضاء هيئة التدريس بقسم أدوية وسموم وطب شرعي بكلية الطب البيطر ابتداء من سنة 2008. يعمل السيد مروان مصطفي دريد بجامعة طرابلس كـأستاذ من 16 اكتوبر 2018 وله العديد من المنشورات العلمية في مجال تخصصه

Publications

Some of publications in Department of Pharmacology, Toxicology & Forensic Medicine

Environmental Conditions Responsible for Hibernation in Mammals

抄録 地球環境の温暖化によって,野生動物の繁殖や冬眠行動が大きな影響を受けることは容易に想像できる。しかし,実際に冬眠がどのような環境条件に影響されているのかは不明である。そこで,本研究では,冬眠行動を誘発する環境条件について検討を行った。冬眠する齧歯目として知られているシリアンハムスターをモデルとして用いた。冬眠の誘発にとって,気温の低下と日照時間の短縮は最も重要な要因であると考えられる。そこで,ハムスターを恒暗・低温環境下で飼育したところ,冬眠に入った。一方,これらの条件に加えて,飼料としてヒマワリの種子や高脂肪食を充分に与えたのち,給餌制限を行った場合,自由摂食をさせた個体と比較して,短期間で冬眠状態に入ることが見いだされた。このことは,食物の量と組成も冬眠行動の誘発に深く関連することを示唆するものである。また,これまでの実験結果から,体重の大きい個体ほど冬眠に入りやすいことがわかった。このことは,体内に蓄積された脂肪細胞から分泌されるレプチンなどのホルモンが,冬眠行動と関連する可能性を示唆するものである。これらの結果から,冬眠は,環境温度や日照時間,そして食物といった外部環境の変化と関連することが示唆された。 It is considered that global warming and exposure to endocrine disrupting chemicals can influence reproduction and hibernation of wildlife. However, environmental factors responsible for such behavioral differences are not well recognized. Therefore, in this study we analyzed environmental conditions that are critical for inducing hibernation. Non-seasonal hibernators, Syrian hamsters were used in this study. It has been pointed out that a low environmental temperature is an important factor to induce hibernation. So, hamsters were kept at a cold room. After about two or three months, they hibernated. Next, food restriction under the cold environment was performed. When the hamsters were fed sunflower seeds or high fat food not standard laboratory chow and then food supply was restricted, they efficiently hibernated in a shorter time period compared with those which were given free access to food. This suggests that the quantity and nutritional composition of food can affect hibernating behavior in addition to a low environmental temperature. We noticed that hibernation is more efficiently induced in obese hamsters than in thin ones. This may indicate that hormones derived from adipose tissue including leptin could be related to hibernation. These results suggest that hibernation might be associated with external environmental factors (environmental temperature and food composition). arabic 6 English 57
Marwan Draid(3-2007)
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Relationship between Body Weight Performance and Plasma Thyroid Hormones in Broiler Hens

o investigate the effect of thyroid hormones Thyroxine (T4) and Triiodothronine (T3) on bodyweight performance in broiler hens. Methodology: The hens were kept in a controlled environment of 50-60% humidity at 31oC in first two weeks than temperature been decreased to 24oC with 24 hr light cycle per day, and were treated gently. Water and feed were provided ad libitum for the all hens. The body weight of the birds detected at the day 2nd, 4th, 6th and 8th week of the experimental period and blood sample detected at the day 14th,28th,42th and 56th day of the experimental period. The data were analyzed by the analysis of variance technique in completely randomized design, while the differences between means were tested by Duncan New Multiple Range Test as per SAS. Results: It was noted that there is a highly significant effect of age, at the level (P ≤ 0.01) on the characteristics of each of the concentration of the hormone T3 and T4 hormone levels and body weight. This study showed that there is a difference in the average concentration of "T4 & T3" for meat birds of different ages. The correlation coefficient manner, "Pearson" between the different qualities of the birds of the meat where it was noted there is a strong inverse relationship between "T4 & T3". arabic 11 English 77
Marwan M. Draid(1-2016)
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Suppressive effect of sulphadimidine on expression of major histocompatibility complex (MHC) in broiler chicken

major histocompatibility complex (MHC) arabic 15 English 96
Marwan Draid(7-2013)
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