An outbreak of gout was investigated in a growing layers farm of 45000 birds located in Tripoli, Libya. Mortality was commenced at 39 days-old reaching to a total of 489 birds within 10 days. Post mortem was conducted and kidney tissue samples were fixed in 10% neutral formalin prior to processing. Feed samples were sent to the Animal Nutrition Department for analysis which revealed 23.47% crude protein and 3.5% calcium. Gross lesions comprised of deposition of chalky white material covering the pericardium and enlarged kidneys with necrotic foci, hemorrhage and nephrosis. Most of birds showed swollen ureter of one or both sides. Histopathologically, severe damage of tubules characterized by moderate to severe tubular dilation and necrosis and central bluish gouty deposition surrounded by radiations of needle like urate crystals followed by granulomatous reaction of lymphocytes, macrophages and fibroblasts. The collecting renal tubules, urinephric ducts and ureters were also filled by gouty deposits with epithelial hyperplastic changes and chronic inflammatory cellular reaction in their walls. The interstitial tissue showed edema, congestion, hemorrhage and lymphomononuclear cell infiltration. This gout outbreak in growing layers is attributed to high concentration of crude protein and calcium in diet.
Ibrahim Eldaghayes(1-2010)

Grouper fish mortality at the East Cost Libyan area of the Mediterranean Sea is one of the major problems encountered at autumn season starting from October. Sudden environmental changes associated with water pollution were recorded. Adult fish especially the grouper types were affected. This phenomenon was previously recorded in Libya at 1985. The present study was carried out to demonstrate the most prevalent isolates that may lead to this phenomenon. It was found that the gram negative oxidase positive bacterial group (Pasteurella, Vibrio and Aeromonas spp.) were the most isolated bacteria with high incidence refers especially to Pasteurella piscicida with an incidence of 64%. Black or metallic colour cysts (Microspordiosis, Glugea spp. and Plistophora spp.) representing spores or larvae of this parasite were observed on the visceral organs and abdominal cavity. Other parasites included larval stages of Contracaecum spp. and Gonapodasmius epinepheli (Didymozoid digenes). The clinical and postmortem lesions were mostly characterized by unilateral or bilateral corneal opacity and haemorrhagic spots on the skin with ulcer formation in some cases. Abdominal distension and anal prolaps were also recorded. All the internal organs were congested. The swim bladder was greatly swollen and filled with gas.
Ibrahim Eldaghayes(9-2011)

Sporadic outbreaks of foot-and-mouth disease (FMD) have occurred in Libya for almost fifty years. During the spring of 2013, a countrywide serosurvey was undertaken to assess the level of FMD virus circulation and identify FMD virus serotypes in the country. A total of 4221 sera were collected, comprising samples from large ruminants (LR; n=1428 samples from 357 farms) and small ruminants (SR; n=2793 samples from 141 farms). FMD sero-prevalence of NSP antibodies determined by ELISA were 19.0% (271/1428) with 95% CI (16.9 – 21.0) and 13.5% (378/2793) with 95% CI (12.3 – 14.8) for LR and SR samples, respectively. The sero-prevalence of NSP antibodies in LR was 12.3% and 19.8% for age group < 1 year and ≥ 1 year, respectively (X2= 4.95, P= 0.026), while in SR was 3.7%, 13.6% and 21.3% for age group < 1 year, 1-2 year and > 2 year, respectively (X2= 118.1, P= 0.000). These observed NSP serologic profiles support the hypothesis of an endemic level of FMD circulation in Libya. All positive sera were tested for SP antibodies for O, A and SAT-2 FMD virus serotypes. Serotype O was the dominant circulating serotype followed by serotype A, while evidence of SAT-2 was not found. These data provide an insight into the wider epidemiology of FMD in Libya, and contribute to field and laboratory investigations that during 2013 serotype O (O/ME-SA/Ind-2001 lineage) was isolated from clinical samples collected from the country.
Ibrahim Eldaghayes(1-2017)