The relationship between ATP-induced membrane potential and contraction was inestigated in the smooth muscle of chicken anterior mesenteric artery using micro-electrode and tension recording techniques respectively. Application of ATP to en-dothelium-denuded arterial preparations developed concentration-dependent, slow depolarization which started only at concentrations not less than 10 μM. On the other hand the tension recording experiment revealed that ATP produced concentration dependent contractions, which were evident at concentrations lower than those evoked depolarizing response to ATP (as lower 100 nM). Both depolarizing & contracting responses were abolished by the P2X receptor blocker, PPADS (50 μM) but not by P2Y receptor blocker CBF3GA (100 μM), indicating that the excitatory responses of ATP were mediated via activation of P2X receptor. These findings suggest that ATP-mediated contraction is not dependent on membrane depolarization only, at least at low concentrations in the first order branches of chicken anterior mesenteric artery. arabic 21 English 153
Marwan Draid(7-2012)

The object of the present study was to assess the possible alterations in blood of sheep that may occur following intramuscular injection of tobramycin. Tobramycin was injected to 10 sheep at a dosage regimen of 5 mg/kg of body weight for 5 successive days. Two types of blood samples (with and without EDTA as an anticoagulant) were collected from the jugular vein before and after the antibiotic course. Tobramycin significantly (p arabic 13 English 83
Marwan Draid(4-2012)

: This study was designed to identify the active contents of Citrullus colocynthis plant and to examine their teratogenicity in rats. The fruit pulp of the poisonous plant was collected randomly from Suq-Alkhamis district, Tripoli, Libya
Amer ELgerwi(8-2013)