More Abstract This work shares Libyan experiences with medical education accreditation, as well as the challenges that the system faced in meeting the criteria of the World Federation of Medical Education (WFME). WFME, which was founded in 1972, is an international organization concerned with the education and training of medical doctors. WFME was initiated on the initiative of the WHO and the World Medical Association (WMA) with the goal of reviewing bodies that accredit basic medical education. The worldwide task force on accreditation in medical education was founded in 2004 by WHO and the WFME. In the same year, 26 members from 23 countries representing all six WHO–WFME regions assembled to discuss how WHO and WFME could assist in the establishment of long-term accrediting systems to ensure high-quality medical education. By 2024, all candidates must obtain a graduation certificate from a program certified by an entity that meets WFME or other international requirements for an accrediting system, according to the Educational Commission for Foreign Medical Graduates. Thereafter, accreditation for all health training programs by 2020 was indorsed as part of the WHO’s Worldwide Strategy on human resources for health: workforce 2030 and was recommended by the WMA. In response to these regulations, the NCQAA has started to prepare “the National Standards Manual for Basic Medical Education” and further connect with all Libyan medical faculties to comply with these criteria, while linking with the WFME. This is based on the WHO endorsement that all countries to apply accreditation mechanisms for health training institutions by 2020. Now it is a time to call for a rigorous auditing system in addition to assessment mechanisms in order to warrant ongoing quality control, and the quality control agency should be self-governing of external encouragement and have only an academic agenda. Finally, all medical schools that have decided to be recognized by the WFME, must have strengthened their ability to face challenges and start adapting these regulations and standards. The construction of networks, alliances, and associations between Libyan medical faculties are encouraged as an efficient approach for implementing and obtaining this accreditation.
Ahmed Elbadri M Atia(11-2021)

one of the main factors that affect the success of the cast crown is the accuracy of the internal and marginal fit, a well-fitting crown reduces the chance for recurrent caries and periodontal disease, whereas the space between a poorly-fitting crown and tooth preparation enables accumulation of bacterial plaque, the use of paint- on die spacing technique to produce the cement gap and subsequently to improve the seating of the cast crowns has become quite popular in the recent years. The purpose of the study is to compare the marginal gap and the internal fit produced by two paint-on die spacing materials (Manicure and paint on die spacer ). Twenty four identical stone dies were made, 12 were coated with paint- on die spacer material, and 12 were coated with nail varnish material, the dies coated with die spacer were divided into three groups (DA,DB,DC), and the dies coated with nail varnish were also divided into three groups (VA,VB,VC), groups DA and VA were coated with one layer, DB and VB were coated with two layers, DC and VC were coated with three layers, for both groups wax patterns were made and casted using the lost waxing technique and all steps were standardized, impression replicas of the casted crowns were made and sectioned by means of the impression replica technique, measurements were taken using Scanning Electron Microscope, from 4 points (marginal gap, mid-axial, axio-occlusal and mid-occlusal). There was no statistical significant difference in accuracy between crowns fabricated on die spacer coated dies and crowns fabricated on nail varnish coated dies. with the crowns fabricated on die spacer coated dies being slightly more accurate.
ABDUSSALAM ELJABALI(12-2019)

The most common preparation of tocotrienols is the tocotrienol-rich fraction (TRF). This study aimed to investigate whether TRF induced liver Nrf2 nuclear translocation and influenced the expression of Nrf2-regulated genes. Methods: In the Nrf2 induction study, mice were divided into control, 2000 mg/kg TRF and diethyl maleate treated groups. After acute treatment, mice were sacrificed at specific time points. Liver nuclear extracts were prepared and Nrf2 nuclear translocation was detected through Western blotting. To determine the effect of increasing doses of TRF on the extent of liver nuclear Nrf2 translocation and its implication on the expression levels of several Nrf2-regulated genes, mice were divided into 5 groups (control, 200, 500 and 1000 mg/kg TRF, and butylated hydroxyanisole-treated groups). After 14 days, mice were sacrificed and liver RNA extracted for qPCR assay. Results: 2000 mg/kg TRF administration initiated Nrf2 nuclear translocation within 30 min, reached maximum level around 1 h and dropped to half-maximal levels by 24 h. Incremental doses of TRF resulted in dose-dependent increases in liver Nrf2 nuclear levels, along with concomitant dose-dependent increases in the expressions of Nrf2-regulated genes. Conclusion: TRF activated the liver Nrf2 pathway resulting in increased expression of Nrf2-regulated cytoprotective genes.
Ahmed Elbadri M Atia(9-2020)