Background and objectives: Allergic rhinitis is common association to asthma according to worldwide studies which showed that control of allergic rhinitis improves in turn asthma symptoms so we have conducted this study looking for the percent of allergic rhinitis in Libyan asthmatic children who were attending regular follow up in asthma clinic of Tripoli children hospital over period of one year (2008). Methods: This study was conducted by asking children’s parents using questionnaire composed of directly answered questions (yes or no) if their children got attacks of rhinorrhea, nasal itching and sneezing around certain times of the year (spring and autumn). Results: Conclusively we found that the incidence of allergic rhinitis in asthmatic Libyan children was 36.6%. Conclusion: allergic rhinitis is common with asthma, and it needs to be put in consideration in any asthma patient and treated accordingly. Cite this article: Elzigallai O, Alrabty H. Study of the Association between Allergic Rhinitis arabic 12 English 82
Hisham Alrabty, Ola Mahmoud Alzigallei(3-2020)

Background: Atopic dermatitis (AD) is a common, chronic, relapsing, itchy, skin condition occurring in patients with a personal or family history of atopy, and there is clinical association among different allergic disease in a way that treating one of them will improve the other. Many studies worldwide showed presence of AD in asthmatic children with different prevalence among countries and showed clinical improvement in asthma control on treatment of atopic dermatitis. Therefore, this study was conducted to assess the prevalence of atopic dermatitis among Libyan asthmatic children. Methods: This is an observational cohort study on asthmatic Libyan children who were treated and followed up at Tripoli children hospital in Tripoli, Libya. It carried out on 300 children suffering from asthma admitted from pediatric outpatient department as well as from emergency department and asthma clinic over a period of 24 months; from December 2017 to December 2019. The parents were asked to complete a questionnaire to collect the needed information after their consent being taken. To assure the accuracy and consistency of the methodology (sampling procedure, measurements, and a collection of the data), a standardized protocol was prepared. Data were entered in SPSS statistical package and consequently were analyzed and presented as descriptive statistics. Results: The prevalence of atopic dermatitis among asthmatic Libyan children was 16.7% in our study. The results showed significant relationship between address and prevalence of atopic dermatitis. Conclusion. Further studies are required to address the ethnicity, environmental factors, skin type and others attributed to this problem and we recommend all pediatricians to look for AD in asthmatic children and treat it accordingly arabic 7 English 56
Hisham Alrabty, Munera Addala(5-2020)

Factor V Leiden G1691A (FVL) and Factor II prothrombin G20210A (PGM) mutations are the leading causes of thrombophilia. In this study, we have investigated the prevalence of the FVL G1691A and PGM G20210A single nucleotide polymorphisms (SNPs) among Libyan deep vein thrombosis (DVT) and myocardial infarction (MI) patients. SNP genotyping was performed using high-resolution melt analysis (HRM) and DNA sequencing. Biochemical parameters conducted on 112 males and 93 females showed no significant difference in means between the control group and the deep vein thrombosis and myocardial infarction groups. For Factor V Leiden, 40 samples were genotyped. Of the 40 samples, 6 (15.0%) of them were heterozygous and no one was homozygous. As for Factor II SNP, 59 samples were genotyped and only 2 (3.3%) were heterozygous. All the heterozygous samples showed 100% concordance between the HRM-PCR and DNA sequence analysis. Our study showed, for the first time, that both the FVL and PGM mutations are present among Libyan DVT and MI patients and that the FVL mutation is significantly associated with DVT but not with MI. However, our results do not support the association of PGM G20210A mutation with DVT or MI. arabic 18 English 117
Abdulghani Msalati, Abdulla Bashein, Murad Ghrew, Khaled Sedaa, Abushawashi Ali, Ahmed Zaid, (1-2021)